Noninvasive Molecular Neuroimaging Using Reporter Genes: Part I, Principles Revisited
نویسندگان
چکیده
منابع مشابه
Noninvasive molecular neuroimaging using reporter genes: part I, principles revisited.
SUMMARY In this first article, we review the basic principles of using reporter genes for molecular imaging of the brain in living subjects. This approach is emerging as a valuable tool for monitoring gene expression in diverse applications in laboratory animals, including the study of gene-targeted and trafficking cells, gene therapies, transgenic animals, and more complex molecular interactio...
متن کاملNoninvasive molecular neuroimaging using reporter genes: part II, experimental, current, and future applications.
SUMMARY In this second article, we review the various strategies and applications that make use of reporter genes for molecular imaging of the brain in living subjects. These approaches are emerging as valuable tools for monitoring gene expression in diverse applications in laboratory animals, including the study of gene-targeted and trafficking cells, gene therapies, transgenic animals, and mo...
متن کاملNoninvasive molecular imaging using reporter genes.
Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging can provide noninvasive assessments of endogenous biologic processes in living subjects and can be performed using different imaging modalities. This review will focus on radionuclide-based reporter gene imaging as developed and applied in preclinical and clinical studies. Examples of different reporter syst...
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Magnetic resonance imaging (MRI) is one of the most important imaging technologies used in clinical diagnosis. Reporter genes for MRI can be applied to accurately track the delivery of cell in cell therapy, evaluate the therapy effect of gene delivery, and monitor tissue/cell-specific microenvironments. Commonly used reporter genes for MRI usually include genes encoding the enzyme (e.g., tyrosi...
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In February 2013, the US Preventive Services Task Force (see www.uspreventiveservicestaskforce.org) recommended 'against daily supplementation with 400 IU or less of vitamin D3 and 1000, mg or less of calcium for the primary prevention of fractures in non institutionalized postmenopausal women', which illustrates the divergence of opinions. This review wants to shed an objective light on the im...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2008
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a0864